Metabolic Autophagy & Hormone Reset
The Science of 16:8 Fasting & Cellular Autophagy
When you fast for 16 consecutive hours, circulating insulin levels plummet, allowing hormone-sensitive lipase to break down stubborn visceral fat into energy while triggering cellular housekeeping.
0 – 4 Hours
Digestion & Glucose Spike
Food is broken down and nutrients are absorbed. Insulin is elevated to transport glucose into cells.
4 – 8 Hours
Insulin Normalization
Insulin levels fall back to baseline. The body begins tapping into liver glycogen reserves.
12 – 14 Hours
Fat Oxidation & Ketones
Glycogen stores are depleted. The liver shifts to lipolysis, creating clean ketone fuel for brain and cardiac tissue.
16+ Hours
Deep Autophagy & Repair
Cells recycle misfolded proteins, dysfunctional mitochondria, and senescent waste (Nobel Prize science).